| 日本側拠点機関名 | 帯広畜産大学 |
| 日本側コーディネーター所属・氏名 | 原虫病研究センター・玄 学南 |
| 研究交流課題名 | マダニ媒介原虫感染症の制圧に向けた国際共同研究拠点の構築 |
| 相手国及び拠点機関名 | ベトナム：フエ大学 タイ：カセサート大学 フィリピン：デラサール大学 スリランカ：獣医学研究所 |
ニュース
- 国際シンポジウムを開催しました 2019年10月
- タイ・バンコクにおいて国際シンポジウムを主催しました。 2018年7月
- 国際シンポジウム開催 2017年7月
研究交流目標
日本側コーディネーターがセンター長を務める帯広畜産大学・原虫病研究センターは、これまでにセンター構成員共通の研究課題として、マダニ媒介性原虫であるバベシア、タイレリア及びマダニそのものに関する研究を設立当初より行ってきた。本センターにはこれら病原体に対する膨大な研究データ、実験技術及び知識が蓄積されており、アジアを代表する研究機関として近隣諸国をリードしている。また、アジア諸国等より受け入れた留学生達を中心にマダニ媒介性原虫病の専門家養成教育を長年施しており、実際に卒業生の多くは帰国後にそれぞれの国を代表する専門家・教育者として活躍している。そこで本事業では、これまでセンターが設立初期から形成して来たアジア諸国（ベトナム、タイ、フィリピン、スリランカ）の研究機関との交流ネットワークを活用し、新たにマダニ媒介原虫感染症の制圧に特化した国際共同研究拠点を構築することを目標とする。すなわち、ゲノム科学に立脚した、各流行地域に適したマダニとマダニ媒介原虫感染症に対する斬新な診断・治療・予防法の創出を通し、開発途上国における家畜生産性向上への貢献を目的とした国際ネットワークのプラットフォームを形成する。さらに、日本側及び相手国側の大学院生・若手研究者を積極的に本事業の中心で活躍させることにより、マダニ媒介原虫感染症の基礎・応用研究に精通したグローバルな若手研究者を育成する。
研究交流計画の概要
①共同研究
❶初年度は、マダニ媒介原虫感染症の流行地域として知られているベトナム中部フエ州、タイ北部チェンマイ州、フィリピン中部セブ島、スリランカ中部州をそれぞれフィールド調査地として選定し、広範囲の実地疫学調査を行う。各流行地域の主要流行原虫株と優占種マダニを特定する。
❷次年度は、上記の主要流行株と優占種マダニについて、次世代シーケンサーを用いた全ゲノム・全トランスクリプトーム解読を行い、独自のデータベースを構築する。これらのデータベースの解析により、各地域の主要流行原虫株を標的とした診断・治療・予防法を考案する。また、優占種マダニを標的としたマダニワクチンとマダニ伝播阻止ワクチンを考案する。
❸最終年度は、上記で考案した各地域に適した迅速簡易血清診断法（ICT法）と核酸診断法（LAMP法）を各海外拠点に導入し、広範囲で応用試験を実施する。また、各種原虫感染症に対する新規治療法とマダニ駆除法について、自然宿主を用いた実験感染系でその効果を検証する。さらに、各種マダニと各種原虫感染症に対する組換えワクチンについて、自然宿主を用いた実験感染系でその効果を検証する。
②セミナー
初年度は日本（帯広）でキックオフセミナーを、次年度はベトナム（フエ）で進捗報告セミナーを、そして最終年度はタイ（バンコク）で事業総括セミナーをそれぞれ行う。これらのセミナーを通じて、拠点構成機関間の協力体制をさらに強化し、また、最新研究成果を次世代研究者へ伝授する。
③研究者交流
文部科学省国費留学生制度、大学独自の奨学金制度、JICA研修員受け入れ制度などを利用して、海外の拠点構成機関から優先的に留学生を受け入れ、将来を見据えた次世代専門家育成を行う。また、日本の若手研究者も積極的に海外拠点構成機関に派遣し、実地疫学調査を体験させる。
実施体制概念図
担当者
研究成果
2020
1. Nakamura C, Liu M, Goo YK, Zhang G, Jia H, Kumagai A, Zhang H, Zhou J, Nishikawa N, Xuan X. Construction of a recombinant vaccinia virus expressing Babesia gibsoni thrombospondin-related anonymous protein and evaluation of its immunogenicity in mice. Trop Biomed, 37: 1029-1037, 2020.
2. Li Y, Galon EM, Guo Q, Rizk MA, Adjou Moumouni PF, Liu L, Li J, Ji S, Chahan B, Xuan X. Molecular detection and identification of Bebesia spp., Theileria spp., and Anaplasma spp. in sheep from border regions, northwetern China. Front Vet Sci, 7: 630, 2020.
3. Tumwebaze MA, Byamukama B, Tayebwa DS, Byaruhanga J, Ringo AE, Adjou Moumouni PF, Li J, Li Y, Ji S, Vudriko P, Xuan X. First molecular detection of Babesia ovis, Theileria spp., Anaplasma spp., and Ehrlichia ruminantium in goats from western Uganda. Pathogens, 9: 895, 2020.
4. Lee SH, Li J, Adjou Moumouni PF, Okado K, Zheng W, Liu M, Ji S, Kim S, Umemiya-Shirafuji R, Xuan X. Subolesin vaccination inhibits blood feeding and reproduction of Haemaphysalis longicornis in rabbits. Parasit Vectors, 13: 478, 2020.
5. Byamukama B, Tumwebaze MA, Tayebwa DS, Byaruhanga J, Angwe MK, Li J, Galon EM, Liu M, Li Y, Ji S, Adjou Moumouni PF, Ringo A, Lee SH, Vudriko P, Xuan X. First molecular detection and characterization of hemotropic Mycoplasma species in cattle and goats from Uganda. Animals, 10: 1624, 2020.
6. Iguchi A, Soma T, Xuan X. Further epidemiological survey for atovaquone resistant related gene of Babesia gibsoni in Japan during 2015-2018. J Vet Med Sci, 82: 1700-1703, 2020.
7. Li J, Jian Y, Jia L, Galon EM, Byamukama B, Wang G, Cai Q, Liu M, Li Y, Ji S, Tumwebaze MA, Ma L, Xuan X. Molecular characterization of tick-borne bacteria and protozoans in yaks (Bos grunniens), Tibetan sheep (Ovis aries) and Bacterian camels (Camelus bacterianus) in the Qinghai-Tibetan Plateau Area, China. Ticks Tick Borne Dis, 11: 101466, 2020.
8. Li Y, Wen X, Li M, Adjou Moumouni PF, Galon EM, Guo Q, Rizk MA, Liu M, Li J, Ji S, Tumwebaze MA, Byamukama B, Chahan B, Xuan X. Molecular detection of tick-borne pthogens harbored by ticks collected from livestock in the Xinjiang Uygur Autonomous rejion, China. Ticks Tick Borne Dis, 11: 101478, 2020.
9. Onyiche TE, Taioe MO, Ogo NI, Sivakumar T, Biu AA, Mbaya AW, Xuan X, Yokoyama N, Thekisoe O. Molecular evidence of Babesia caballi and Theileria equi in equines and ticks in Nigeria: prevalence and risk factors analysis. Parasitology, 147: 1238-1248, 2020.
10. Ringo A, Rizk MA, Adjou Moumouni PF, Liu M, Galon EM, Li Y, Ji S, Tumwebaze M, Byamukama B, Thekisoe O, Xuan X. Molecular detection and characterization of tick-borne haemoparasites among cattle on Zanzibar Island, Tanzania. Acta Tropica, 210: 105598, 2020.
11. Zheng W, Umemiya-Shirafuji R, Zhang Q, Okado K, Adjou Moumouni PF, Suzuki H, Chen H, Liu M, Xuan X. Porin expression profiles in Haemaphysalis longicornis infected with Babesia microti. Front Physiol, 11: 502, 2020.
12. Tumwebaze MA, Lee SH, Adjou Moumouni PF, Mohammed-Geba K, Sheir SK, Galal-Khallaf A, Abd El Latif HM, Morsi DS, Bishr NM, Galon EM, Byamukama B, Liu M, Li J, Li L, Ji S, Ringo AE, Rizk MA, Suzuki H, Ibrahim HA, Xuan X. First detection of Anaplasma ovis in sheep and Anaplasma platys-like variants from cattle in Menoufia governorate, Egypt. Parasitol Int, 78: 102150, 2020.
13. Zheng W, Umemiya-Shirafuji R, Chen S, Okado K, Adjou Moumouni PF, Suzuki H, Yang S, Liu M, Xuan X. Identification of Haemaphysalis longicornis genes differentially expressed in response to Babesia microti infection. Pathogens, 9: 378, 2020.
14. Galon EM, Ybanez RH, Adjou Moumouni PF, Tumwebaze MA, Fabon RJA, Callanta MRR, Labutong KJE, Salazar GB, Liu M, Li J, Byamukama B, Li Y, Ji S, Lee SH, Ybanez AP, Claveria FG, Xuan X. Molecular survey of tick-borne pathogens infecting backyard cattle and water buffaloes in Quezon province, Philippines. J Vet Med Sci, 82: 886-890, 2020.
15. Efstratiou A, Galon EM, Wang G, Umeda K, Kondoh D, Terkawi MA, Kume A, Liu L, Ringo AE, Guo H, Gao Y, Lee SH, Li J, Adjou Moumouni PF, Nishikawa Y, Suzuki H, Igarashi I, Xuan X. Babesia microti confers macrophage-babed cross-protective immunity against murine malaria. Front Cell Infect Microbiol, 10: 193, 2020.
16. Byamukama B, Ceylan O, Adjou Moumouni PF, Lee SH, Tumwebaze MA, Li J, Galon EM, Liu M, Li Y, Ji S, Ringo A, Rizk MA, Sevinc F, Xuan X. Molecular detection and assessment of risk factors for tick-borne diseases in sheep and goats from Turkey. Acta Parasitol, 65: 723-732, 2020.
17. Jian Y, Li J, Adjou Moumouni PF, Zhang X, Tumwebaze MA, Wang G, Cai Q, Li X, Wang G, Liu M, Li Y, Ma L, Xuan X. Human spotted fever group Rickettsia infecting yaks (Bos grunniens) in the Qinghai-Tibetan plateau area. Pathogen, 9: e249, 2020.
18. Liu M, Ji S, Rizk MA, Adjou Moumouni PF, Galon EM, Li J, Li Y, Zheng W, Byamukama B, Tumwebaze MA, Asada M, Xuan X. Transient transfection of the zoonotic parasite Babesia microti. Pathogens, 9: e108, 2020.
19. Elata A, Mossaad E, Satti R, Matar N, Ohari Y, Xuan X, Inoue N, Suganuma K. Serological and molecular detection of selected hemoprotozoan parasites in donkeys in West Omdurman, Khartoum State, Sudan. J Vet Med Sci, 82: 286-293, 2020.
20. Rizk MA, Ji S, Liu M, El-Sayed SAE, Li Y, Byamukama B, Ringo A, Xuan X, Ikuo Igarashi. Closing the empty anti-Babesia gibsoni drug pipeline in vitro using fluorescence-based high throughput screening assay. Parasitol Int, 75: 102054, 2020.
21. Li Y, Liu M, Rizk MA, Adjou Moumouni PF, Lee SH, Galon EM, Guo H, Gao Y, Li J, Beshbishy AM, Nugraha AB, Ji S, Tumwebaze MA, Byamukama B, Yokoyama N, Igarashi I, Xuan X. Drug screening of food and drug administration-approved compounds against Babesia bovis in vitro. Exp Parasitol, 210: 107831, 2020.
22. Li J, Li Y, Adjou Moumouni PF, Lee SH, Galon EM, Tumwebaze MA, Yang H, Huercha, Liu M, Guo H, Gao Y, Byamukama B, Zhang W, Fan X, Chahan B, Xuan X. First description of Coxiella burnetii and Rickettsia spp. infection and molecular detection of piroplasma co-infecting horses in Xinjiang Uygur Autonomous Region, China. Parasitol Int, 76: 102028, 2020.
23. Li Y, Li J, Chahan B, Guo Q, Zhang Y, Moumouni PFA, Lee SH, Liu M, Galon EM, Guo H, Gao Y, Song R, Li M, Tumwebaze MA, Benedicto B, Xuan X. Molecular investigation of tick-borne infections in cattle from Xinjiang Uygur Autonomous Resion, China. Parasitol Int, 74: 101925, 2020.
24. Rizk MA, El-Sayed SAE, Nassif M, Mosqueda M, Xuan X, Ikuo garashi. Assay methods for in vitro and in vivo anti-Babesia drug efficacy testing: Current progress, outlook, and challenges. Vet Parasitol, 279: 109013, 2020.
2019
25. Ybañez AP, Arrabis OV, Alvarez DJM, Galon EMS, Jayag RMP, Delan ES, Ybañez RHD, Xuan X. Evaluation on the presence of Anaplasma, Ehrlichia, and Babesia spp. in goats (Capra hircus) in Cebu, the Philippines. Vet World, 12: 774-777, 2019.
26. Ringo AE, Aboge GO, Adjou Moumouni PF, Hun Lee S, Jirapattharasate C, Liu M, Gao Y, Guo H, Zheng W, Efstratiou A, Galon EM, Li J, Thekisoe O, Inoue N, Suzuki H, Xuan X. Molecular detection and genetic characterisation of pathogenic Theileria, Anaplasma and Ehrlichia species among apparently healthy sheep in central and western Kenya. Onderstepoort J Vet Res, 86: e1-e8, 2019.
27. Onyiche TE, Suganuma K, Igarashi I, Yokoyama N, Xuan X, Thekisoe O. A eview on equine piroplasmosis: Epidemiology, vector ecology, risk factors, host immunity, diagnosis and control. Int J Environ Res Public Health, 16: 10, 2019.
28. Guo H, Adjou Moumouni PF, Thekisoe O, Gao Y, Liu M, Li J, Galon EM, Efstratiou A, Wang G, Jirapattharasate C, Ringo AE, Mtshali K, Inoue N, Suzuki H, Xuan X. Genetic characterization of tick-borne pathogens in ticks infesting cattle and sheep from three South African provinces. Ticks Tick Borne Dis, 10: 875-882, 2019.
29. Galon EMS, Adjou Moumouni PF, Ybañez RHD, Ringo AE, Efstratiou A, Lee SH, Liu M, Guo H, Gao Y, Li J, Salces CB, Maurillo BCA, Boldbaatar D, Ybañez AP, Xuan X. First molecular detection and characterization of tick-borne pathogens in water buffaloes in Bohol, Philippines. Ticks Tick Borne Dis, 10: 815-821, 2019.
30. Galon EMS, Adjou Moumouni PF, Ybañez RHD, Macalanda AMC, Liu M, Efstratiou A, Ringo AE, Lee SH, Gao Y, Guo H, Li J, Tumwebaze MA, Byamukama B, Li Y, Ybañez AP, Xuan X. Molecular evidence of hemotropic mycoplasmas in goats from Cebu, Philippines. J Vet Med Sci, 81: 869-873, 2019.
31. Lee SH, Moumouni PFA, Galon EM, Vudriko P, Liu M, Benedicto B, Tumwebaze MA, Boldbaatar D, Umemiya-Shirafuji R, Fukumoto S, Xuan X. Differential diagnosis and molecular characterization of Theileria spp. in sika deer (Cervus nippon) in Hokkaido, Japan. Parasitol Int, 70: 23-26, 2019.
32. Liu M, Masatani T, Adjou Moumouni PF, Lee SH, Galon EM, Gao Y, Guo H, Li J, Li Y, Xuan X. Inhibitory effects of the phytohormone inhibitors fluridone and inabenfide against Babesia gibsoni in vitro. Vet Parasitol, 265: 19-23, 2019.
33. Zheng W, Xuan X, Fu R, Tao H, Xu R, Liu Y, Liu X, Jiang J, Wu H, Ma H, Sun Y, Chen H. Preliminary investigation of ixodid ticks in Jiangxi Province of Eastern China. Exp Appl Acarol, 77: 93-104, 2019.
2018
34. Ringo AE, Adjou Moumouni PF, Lee SH, Liu M, Khamis YH, Gao Y, Guo H, Zheng W, Efstratiou A, Galon EM, Li J, Tiwananthagorn S, Inoue N, Suzuki H, Thekisoe O, Xuan X. Molecular detection and characterization of tick-borne protozoan and rickettsial pathogens isolated from cattle on Pemba Island, Tanzania. Ticks Tick Borne Dis, 9: 1437-1445, 2018.
35. Vudriko P, Umemiya-Shirafuji R, Okwee-Acai J, Tayebwa DS, Byaruhanga J, Bbira JS, Fujisaki K, Xuan X, Suzuki H. C190A knockdown mutation in sodium channel domain II of pyrethroid-resistant Rhipicephalus appendiculatus. Ticks Tick Borne Dis, 9: 1590-1593, 2018.
36. Guo H, Yin C, Galon EM, Du J, Gao Y, Adjou Moumouni PF, Liu M, Efstratiou A, Lee SH, Li J, Ringo AE, Wang G, Li Y, Tumwebaze MA, Xuan X. Molecular survey and characterization of Theileria annulata and Ehrlichia ruminantium in cattle from Northwest China. Parasitol Int, 67: 679-683, 2018.
37. Ybañez AP, Ybañez RHD, Talle MG, Arreglo RMT, Geens MJC, Villas JGI 3rd, Villar SR, Laruga CL, Cao S, Moumouni FPA, Liu M, Igarashi I, Xuan X. Serological and molecular detection of Theileria equi and Babesia caballi in Philippine horses. Ticks Tick Borne Dis, 9: 1125-1128, 2018.
38. Liu M, Adjou Moumouni PF, Asada M, Hakimi H, Masatani T, Vudriko P, Lee SH, Kawazu SI, Yamagishi J, Xuan X. Establishment of a stable transfection system for genetic manipulation of Babesia gibsoni. Parasit Vectors, 11: 260, 2018.
39. Wang G, Yu L, Efstratiou A, Moumouni PFA, Liu M, Guo H, Gao Y, Cao S, Zhou M, Li J, Ringo AE, Xuan X. Evaluation of the protective effect of a prime-boost strategy with plasmid DNA followed by recombinant adenovirus expressing BmAMA1 as vaccines against Babesia microti infection in hamster. Acta Parasitol, 63: 368-374, 2018.
40. Adjou Moumouni PF, Aplogan GL, Katahira H, Gao Y, Guo H, Efstratiou A, Jirapattharasate C, Wang G, Liu M, Ringo AE, Umemiya-Shirafuji R, Suzuki H, Xuan X. Prevalence, risk factors, and genetic diversity of veterinary important tick-borne pathogens in cattle from Rhipicephalus microplus-invaded and non-invaded areas of Benin. Ticks Tick Borne Dis, 9: 450-464, 2018.
41. Sevinc F, Zhou M, Cao S, Ceylan O, Aydin MF, Sevinc M, Xuan X. Haemoparasitic agents associated with ovine babesiosis: A possible negative interaction between Babesia ovis and Theileria ovis. Vet Parasitol, 252: 143-147, 2018.
42. Zheng W, Liu Y, Tao H, Li Z, Xuan X, Liu X, Adjou Moumouni PF, Wu Y, Liu W, Chen H. First molecular evidence of Anaplasma phagocytophilum in rodent populations of Nanchang, China. Jpn J Infect Dis, 71: 129-133, 2018.
43. Ybañez RHD, Ybañez AP, Arnado LLA, Belarmino LMP, Malingin KGF, Cabilete PBC, Amores ZRO, Talle MG, Liu M, Xuan X. Detection of Ehrlichia, Anaplasma, and Babesia spp. in dogs of Cebu, Philippines. Vet World, 11: 14-19, 2018.
44. Lee SH, Mossaad E, Ibrahim AM, Ismail AA, Adjou Moumouni PF, Liu M, Ringo AE, Gao Y, Guo H, Li J, Efstratiou A, Musinguzi P, Angara TEE, Suganuma K, Inoue N, Xuan X. Detection and molecular characterization of tick-borne pathogens infecting sheep and goats in Blue Nile and West Kordofan states in Sudan. Ticks Tick Borne Dis, 9: 598-604, 2018.
45. Liu M, Adjou Moumouni PF, Cao S, Asada M, Wang G, Gao Y, Guo H, Li J, Vudriko P, Efstratiou A, Ringo AE, Lee SH, Hakimi H, Masatani T, Sunaga F, Kawazu SI, Yamagishi J, Jia L, Inoue N, Xuan X. Identification and characterization of interchangeable cross-species functional promoters between Babesia gibsoni and Babesia bovis. Ticks Tick Borne Dis, 9: 330-333, 2018.
46. Ringo AE, Adjou Moumouni PF, Taioe M, Jirapattharasate C, Liu M, Wang G, Gao Y, Guo H, Lee SH, Zheng W, Efstratiou A, Li J, Inoue N, Suzuki H, Thekisoe O, Xuan X. Molecular analysis of tick-borne protozoan and rickettsial pathogens in small ruminants from two South African provinces. Parasitol Int, 67: 144-149, 2018.
47. Vudriko P, Okwee-Acai J, Byaruhanga J, Tayebwa DS, Okech SG, Tweyongyere R, Wampande EM, Okurut ARA, Mugabi K, Muhindo JB, Nakavuma JL, Umemiya-Shirafuji R, Xuan X, Suzuki H. Chemical tick control practices in southwestern and northwestern Uganda. Ticks Tick Borne Dis, 9: 945-955, 2018.
48. Vudriko P, Okwee-Acai J, Byaruhanga J, Tayebwa DS, Omara R, Muhindo JB, Lagu C, Umemiya-Shirafuji R, Xuan X, Suzuki H. Evidence-based tick acaricide resistance intervention strategy in Uganda: Concept and feedback of farmers and stakeholders. Ticks Tick Borne Dis, 9: 254-265, 2018.
49. Adjou Moumouni PF, Guo H, Gao Y, Liu M, Ringo AE, Galon EM, Vudriko P, Umemiya-Shirafuji R, Inoue N, Suzuki H, Xuan X. Identification and genetic characterization of Piroplasmida and Anaplasmataceae agents in feeding Amblyomma variegatum ticks from Benin. Vet Parasitol Reg Stud Reports, 14: 137-143, 2018.
2017
50. Liu M, Asada M, Cao S, Adjou Moumouni PF, Vudriko P, Efstratiou A, Hakimi H, Masatani T, Sunaga F, Kawazu SI, Yamagishi J, Xuan X. Transient transfection of intraerythrocytic Babesia gibsoni using elongation factor-1 alpha promoter. Mol Biochem Parasitol, 216: 56-59, 2017.
51. Liu MM, Jia LJ, Cao SN, Adjou Moumouni PF, Jirapattharasate C, Wang GB, Gao Y, Guo HP, Zhou M, Yu LZ, Xue SJ, Xuan XN. Molecular detection of Theileria species in cattle from Jilin province, China. Trop Biomed, 34: 598-606, 2017.
52. Vudriko P, Umemiya-Shirafuji R, Okwee-Acai J, Tayebwa DS, Byaruhanga J, Jirapattharasate C, Liu M, Adjou Moumouni PF, Fujisaki K, Xuan X, Suzuki H. Genetic mutations in sodium channel domain II and carboxylesterase genes associated with phenotypic resistance against synthetic pyrethroids by Rhipicephalus (Boophilus) decoloratus ticks in Uganda. Pestic Biochem Physiol, 143: 181-190, 2017.
53. Mousa AA, Roche DB, Terkawi MA, Kameyama K, Kamyingkird K, Vudriko P, Salama A, Cao S, Orabi S, Khalifa H, Ahmed M, Attia M, Elkirdasy A, Nishikawa Y, Xuan X, Cornillot E. Human babesiosis: Indication of a molecular mimicry between thrombospondin domains from a novel Babesia microti BmP53 protein and host platelets molecules. PLoS One, 12: e0189383, 2017.
54. Kamiyingkird K, Cao S, Tuvshintulga B, Salama A, Mousa AA, Efstratiou A, Nishikawa Y, Yokoyama N, Igarashi I, Xuan X. Effects of dihydroorotate dehydrogennase (DHODH) inhibitors on the growth of Theileria equi and Babesia caballi in vitro. Exp Parasitol, 176: 59-65, 2017.
55. Guo H, Sevinc F, Ceylan O, Sevinc M, Ince E, Gao Y, Moumouni PFA, Liu M, Efstratiou A, Wang G, Cao S, Zhou M, Jirapattharasate C, Ringo AE, Zheng W, Xuan X. A PCR survey of vector-borne pathogens in different dog populations from Turkey. Acta Parasitol, 62: 533-540, 2017.
56. Zhou M, Cao S, Sevinc F, Sevinc M, Ceylan O, Ekici S, Jirapattharasate C, Moumouni PF, Liu M, Wang G, Iguchi A, Vudriko P, Suzuki H, Xuan X. Molecular detection and genetic characterization of Babesia, Theileria and Anaplasma amongst apparently healthy sheep and goats in the central region of Turkey. Ticks Tick Borne Dis, 8: 246-252, 2017.
57. Jirapattharasate C, Adjou Moumouni PF, Cao S, Iguchi A, Liu M, Wang G, Zhou M, Vudriko P, Efstratiou A, Changbunjiong T, Sungpradit S, Ratanakorn P, Moonarmart W, Sedwisai P, Weluwanarak T, Wongsawang W, Suzuki H, Xuan X. Molecular detection and genetic diversity of bovine Babesia spp., Theileria orientalis, and Anaplasma marginale in beef cattle in Thailand. Parasitol Res, 116: 751-762, 2017.
58. Zheng W, Liu M, Moumouni PF, Liu X, Efstratiou A, Liu Z, Liu Y, Tao H, Guo H, Wang G, Gao Y, Li Z, Ringo AE, Jirapattharasate C, Chen H, Xuan X. First molecular detection of tick-borne pathogens in dogs from Jiangxi, China. J Vet Med Sci, 79: 248-254, 2017.
59. Wang G, Efstratiou A, Adjou Moumouni PF, Liu M, Jirapattharasate C, Guo H, Gao Y, Cao S, Mo Zhou, Suzuki H, Igarashi I, Xuan X. Expression of truncated Babesia microti apical membrane protein 1 and rhoptry neck protein 2 and evaluation of their protective efficacy. Exp Parasitol, 172: 5-11, 2017.
60. Ybañez AP, Ybañez RH, Talle MG, Liu M, Moumouni PF, Xuan X. First report on Babesia vogeli infection in dogs in the Philippines. Parasitol Int, 66: 813-815, 2017.