寄附講座: 生命平衡科学講座

概要

名称

生命平衡科学講座(白寿)第3期

設置期間

2020年11月1日~2025年3月31日(4年5か月間)

寄附者

株式会社白寿生科学研究所
代表取締役社長 原 浩之(はら ひろゆき)

講座趣意

 我が国では超高齢化社会に突入以降、医療費の増大とその原資不足への懸念から予防医学の発展への期待が大きく、生命がその誕生から終末まで本来持つ生体機能を平衡に保つ働きについての総合的研究の拡充が望まれます。生命平衡科学講座(白寿)においては、超低周波(ELF)電界の生体への影響・効果に着目し、生殖系・免疫系・内分泌系・神経系における電界の作用点の探索と機能解析を行い、その結果、ELF電界が多くの疾患の原因となるストレスおよび炎症に対し有効性を示すことを突き止め、その効果の最適化のための電界デザイン(仕様)の整理を展開しています。電界によるストレス応答への抑制的効果は、身体的フレイルだけでなく社会的フレイル対策を含む予防医学への応用可能性を有すと考えられ、当講座では今後も国民の健康寿命の延伸に資する、さらなる研究と実用的技術の開発を進めます。

寄附予定総額

2千5百万円

スタッフ

職名 氏名 連絡先
教授(併任) 鈴木 宏志 hisuzuki
客員教授 原川 信二 sharakawa_hakuju

※メールアドレスは,@obihiro.ac.jpを省略してあります

研究成果

1 論文

Shinba T, Nedachi T, Harakawa S. 2021. Extremely Low‐Frequency Electric Field Exposure Increases Theta Power of EEG in both Eyes‐Open and Eyes‐Closed Resting Conditions in Healthy Male Subjects. IEEJ Transactions on Electrical and Electronic Engineering 16:592–599. New! (2021.4)
https://doi.org/10.1002/tee.23334
https://research-er.jp/articles/view/98303

Harakawa S, Nedachi T, Suzuki H. 2020. Extremely low-frequency electric field suppresses not only induced stress response but also stress-related tissue damage in mice. Sci Rep 10:20930. New! (2021.4)
https://doi.org/10.1038/s41598-020-76106-1
https://research-er.jp/articles/view/94732

Harakawa S, Nedachi T, Suzuki H. Extremely low-frequency electric field suppresses not only induced stress response but also stress-related tissue damage in mice. Scientific Reports (in press)

Harakawa S, Hori T, Nedachi T, Suzuki H. 2020. Gender and Age Differences in the Suppressive Effect of a 50 Hz Electric Field on the Immobilization-Induced Increase of Plasma Glucocorticoid in Mice. Bioelectromagnetics 41:156–163.

Hori T, Nedachi T, Suzuki H, Harakawa S. 2018. Characterization of the suppressive effects of extremely-low-frequency electric fields on a stress-induced increase in the plasma glucocorticoid level in mice. Bioelectromagnetics 39:516-528.

Harakawa S, Hori T, Inoue N, Suzuki H. 2017. Time-dependent changes in the suppressive effect of electric field exposure on immobilization-induced plasma glucocorticoid increase in mice. Bioelectromagnetics 38:272-279.

Hori T, Inoue N, Suzuki H, Harakawa S. 2017. Configuration-dependent variability of the effect of an electric field on the plasma glucocorticoid level in immobilized mice. Bioelectromagnetics 38:265-271.

Hori T, Inoue N, Suzuki H, Harakawa S. 2015. Exposure to 50 Hz electric fields reduces stress-induced glucocorticoid levels in BALB/c mice in a kV/m- and duration-dependent manner. Bioelectromagnetics 36:302-308.

Tsuchiya M, Shiozawa T, Harakawa S. 2014. Electric field sensing and imaging by noninvasive parallel-plate sensor. IEICE Electronics Express 11:1-7.

Harakawa S, Hori T, Inoue N, Okano H, Nedachi T, Suzuki H. 2014. Effect of extensive electric field therapy in bone density. JIM 7:60-66.

Hori T, Harakawa S, Herbas SM, Ueta YY, Inoue N, Suzuki H. 2012. Effect of 50 Hz electric field in diacylglycerol acyltransferase mRNA expression level and plasma concentration of triacylglycerol, free fatty acid, phospholipid and total cholesterol. Lipids Health Dis 11:68.

Shinba T, Takahashi K, Kanetake S, Nedachi T, Yamaneki M, Doge F, Hori T, Harakawa S, Miki M, Hara H, Suzuki H, Hara A. 2012. A pilot study on electric field therapy for chronic pain with no obvious underlying diseases. JIM 5:68-72.

2 学会発表

Hori T, Nedachi T, Suzuki H, Harakawa S. 2018. Characterization of the suppressive effects of extremely-low-frequency electric fields on a stress-induced increase in the plasma glucocorticoid level in mice. The Joint Annual Meeting of The Bioelectromagnetics Society and the European BioElectromagnetics Association PA-107.

Hori T, Suzuki H, Harakawa S. 2017. Anti-stress effects of exposure to a 50-Hz electric field in immobilized mice. The Joint Annual Meeting of The Bioelectromagnetics Society and the European BioElectromagnetics Association PA-93.

甲田道明,下原光幸,貴志俊英,原川信二,(2016)高圧ケーブル端末部の電界イメージング. 電気学会全国大会講演論文集ROMBUNNO.1‐026

Harakawa S, Hori T, Tsuchiya, M. 2014. Environmental Assessment by Electric Field Imager. IEIEJ 32: F21.

Hori T, Inoue N, Suzuki H, Harakawa S. 2014. Effect of electric field that depresses an increase of plasma glucocorticoid induced by restriction, in general blood property, biochemistry and body weight. J Jpn Biomag Bioelectromag Soc 27: 74-75.

Hori T, Inoue I, Suzuki H, Harakawa S. 2013. Dose-dependent effects of exposure to electric field on plasma corticosterone level in restricted mice. J Jpn Biomag Bioelectromag Soc 26: 259-260.

Hori T, Harakawa S, Inoue I, H S. 2012. Dose dependent effect of electric field in plasma corticosterone level on restricted mice. J Jpn Biomag Bioelectromag Soc 25(1): 222-223.

3 特許

特許 2016-076088 検知出力装置及び可視化装置 出願中
特許 2016-076089 電界検知出力装置 出願中
特許 2017-005390 検知出力装置 特許査定 登録 (日本). New! (2021.4)
https://jglobal.jst.go.jp/detail?JGLOBAL_ID=201803007271553609
特許 2015-559102 電界検知出力装置 特許査定 登録 (日本、中国、台湾)
特許 2014-145446 可視化装置および可視化方法 特許査定 登録 (日本、中国、台湾)
特許 2015-231165 電界調整システム 特許査定 登録

小動物実験用の電界曝露装置
電界曝露実験
細胞への電界処置
fish exposed to EF within an EF chamber
dog exposed to 50 Hz Electric field
visualized Electric Field