WOAH reference laboratory for bovine babesiosis

Recent publications

  1. Tayebwa, D.S., Beshbishy, A.M., Batiha, G.E., Komugisha, M., Joseph, B., Vudriko, P., Yahia, R., Alkazmi, L., Hetta, H.F., Yokoyama, N., Igarashi, I. 2020. Assessing the immunochromatographic test strip for serological detection of bovine babesiosis in Uganda. Microorganisms 8, 1110.
  2. Carvalho, L.J.M, Tuvshintulga, B., Nugraha, A.B., Sivakumar, T., Yokoyama, N., 2020. Activities of artesunate-based combinations and tafenoquine against Babesia bovis in vitro and Babesia microti in vivo. Parasit. Vectors 13, 362.
  3. Batiha, G.E., Tayebwa, D.S., Beshbishy, A.M., N’Da, D.D., Yokoyama, N., Igarashi, I. 2020. Inhibitory effects of novel ciprofloxacin derivatives on the growth of four Babesia species and Theileria equi. Parasitol. Res. 119, 3061–3073.
  4. Otgonsuren, D., Sivakumar, T., Amgalanbaatar, T., Enkhtaivan, B., Narantsatsral, S., Tuvshintulga, B., Zoljargal, M., Munkhgerel, D., Davkharbayar, B., Baatarjargal, P., Davaasuren, B., Myagmarsuren, P., Battsetseg, B., Battur, B., Yokoyama, N. 2020. Molecular epidemiological survey of Babesia bovis, Babesia bigemina, and Babesia Mymensingh infections in Mongolian cattle. Parasitol. Int. 77, 102107.
  5. Sivakumar, T., Tuvshintulga, B., Kothalawala, H., Silva, S.S.P., Lan, D.T.B., Long, P.T., Ybañez, A.P., Ybañez, R.H.D., Benitez, D.F., Tayebwa, D.S., De Macedo, A.C.C., Schnittger, L., Yokoyama, N. 2020. Host range and geographical distribution of Babesia Mymensingh. Transbound. Emerg. Dis. 67, 2233–2239.
  6. Beshbishy, A.M., Batiha, G.E., Alkazmi, L., Nadwa, E., Rashwan, E., Abdeen, A., Yokoyama, N., Igarashi, I. 2020. Therapeutic effects of atranorin towards the proliferation of Babesia and Theileria Pathogens 9, 127.
  7. Batiha, G.E., Beshbishy, A.M., Adeyemi, O.S., Nadwa, E., Rashwan, E., Yokoyama, N., Igarashi, I. 2020. Safety and efficacy of hydroxyurea and eflornithine against most blood parasites Babesia and Theileria. PLoS One. 15, e0228996.
  8. Li, Y., Liu, M., Rizk, M.A., Moumouni, P.F.A., Lee, S.H., Galon, E.M., Guo, H., Gao, Y., Li, J., Beshbishy, A.M., Nugraha, A.B., Ji, S., Tumwebaze, M.A., Benedicto, B., Yokoyama, N., Igarashi, I., Xuan, X. 2020. Drug screening of food and drug administration-approved compounds against Babesia bovis in vitro. Exp. Parasitol. 210, 107831.
  9. Rizk MA, El-Sayed SAE, El-Khodery S, Yokoyama N, Igarashi I. 2019. Discovering the in vitro potent inhibitors against Babesia and Theileria parasites by repurposing the Malaria Box: A review. Vet. Parasitol. 274, 108895.
  10. Batiha, G.E., Beshbishy, A.M., Tayebwa, D.S., Adeyemi, O.S., Yokoyama, N., Igarashi, I. 2019. Evaluation of the inhibitory effect of ivermectin on the growth of Babesia and Theileria parasites in vitro and in vivo. Trop. Med. Health 47, 42.
  11. Nugraha, A.B., Tuvshintulga, B., Guswanto, A., Tayebwa, D.S., Rizk, M.A., Gantuya, S., Batiha, G.E., Beshbishy, A.M., Sivakumar, T., Yokoyama, N., Igarashi I. 2019. Screening the Medicines for Malaria Venture Pathogen Box against piroplasm parasites. Int. J. Parasitol. Drugs Drug Resist. 10, 84–90
  12. Beshbishy, A.M., Batiha, G.E., Yokoyama, N., Igarashi, I. 2019. Ellagic acid microspheres restrict the growth of Babesia and Theileria in vitro and Babesia microti in vivo. Parasit. Vectors 12, 269.
  13. Batiha, G.E., Beshbishy, A.M., Tayebwa, D.S., Adeyemi, O.S., Shaheen, H., Yokoyama, N., Igarashi I. 2019. The effects of trans-chalcone and chalcone 4 hydrate on the growth of Babesia and Theileria. PLoS Negl. Trop. Dis. 13, e0007030.
  14. Batiha, G.E., Beshbishy, A.M., Tayebwa, D.S., Shaheen, H.M., Yokoyama, N., Igarashi, I. 2019. Inhibitory effects of Syzygium aromaticum and Camellia sinensis methanolic extracts on the growth of Babesia and Theileria Ticks Tick Borne Dis. 10, 949–958.
  15. Gunasekara, E., Sivakumar, T., Kothalawala, H., Abeysekera, T.S., Weerasingha, A.S., Vimalakumar, S.C., Kanagaratnam, R., Yapa, P.R., Zhyldyz, A., Igarashi, I., Silva, S.S.P., Yokoyama, N. 2019. Epidemiological survey of hemoprotozoan parasites in cattle from low-country wet zone in Sri Lanka. Parasitol. Int. 71, 5–10.
  16. Tuvshintulga, B., Sivakumar, T., Yokoyama, N., Igarashi, I. 2019. Development of unstable resistance to diminazene aceturate in Babesia bovis. Int. J. Parasitol. Drugs Drug Resist. 9, 87–92.
  17. El-Sayed, S.A.E., Rizk, M.A., Yokoyama, N., Igarashi, I. 2019. Evaluation of the in vitro and in vivo inhibitory effect of thymoquinone on piroplasm parasites. Parasit. Vectors. 12, 37.
  18. Rizk, M.A., AbouLaila, M., El-Sayed, S.A.E., Guswanto, A., Yokoyama, N., Igarashi, I. 2018. Inhibitory effects of fluoroquinolone antibiotics on Babesia divergens and Babesia microti, blood parasites of veterinary and zoonotic importance. Infect. Drug Resist. 11, 1605–1615.
  19. Sivakumar, T., Tuvshintulga, B., Zhyldyz, A., Kothalawala, H., Yapa, P.R., Kanagaratnam, R., Vimalakumar, S.C., Abeysekera, T.S., Weerasingha, A.S., Yamagishi, J., Igarashi, I., Silva, S.S.P., Yokoyama, N. 2018. Genetic analysis of Babesia isolates from cattle with clinical babesiosis in Sri Lanka. J. Clin. Microbiol. 56, e00895–18.
  20. Tayebwa, D.S., Vudriko, P., Tuvshintulga, B., Guswanto, A., Nugraha, A.B., Gantuya, S., Batiha, G.E., Musinguzi, S.P., Komugisha, M., Bbira, J.S., Okwee-Acai, J., Tweyongyere, R., Wampande, E.M., Byaruhanga, J., Adjou Moumouni, P.F., Sivakumar, T., Yokoyama, N., Igarashi, I. 2018. Molecular epidemiology of Babesia species, Theileria parva, and Anaplasma marginale infecting cattle and the tick control malpractices in Central and Eastern Uganda. Ticks Tick Borne Dis. 9, 1475–1483.
  21. Tayebwa, D.S., Tuvshintulga, B., Guswanto, A., Nugraha, A.B., Batiha, G.E., Gantuya, S., Rizk, M.A., Vudriko, P., Sivakumar, T., Yokoyama, N., Igarashi, I. 2018. The effects of nitidine chloride and camptothecin on the growth of Babesia and Theileria Ticks Tick Borne Dis. 9, 1192–1201.
  22. Umemiya-Shirafuji, R., Hatta, T., Okubo, K., Sato, M., Maeda, H., Kume, A., Yokoyama, N., Igarashi, I., Tsuji, N., Fujisaki, K., Inoue, N., Suzuki, H. 2018. Transovarial persistence of Babesia ovata DNA in a hard tick, Haemaphysalis longicornis, in a semi-artificial mouse skin membrane feeding system. Acta Parasitol. 63, 433.
  23. Guswanto, A., Nugraha, A.B., Tuvshintulga, B., Tayebwa, D.S., Rizk, M.A., Batiha, G.E., Gantuya, S., Sivakumar, T., Yokoyama, N., Igarashi, I. 2018. 17-DMAG inhibits the multiplication of several Babesia species and Theileria equi on in vitro cultures, and Babesia microti in mice. Int. J. Parasitol. Drugs Drug Resist. 8, 104–111.
  24. Battsetseg, B., Sivakumar, T., Naranbaatar, K., Narantsatsral, S., Myagmarsuren, P., Enkhtaivan, B., Davaasuren, B., Mizushima, D., Weerasooriya, G., Igarashi, I., Battur, B., Yokoyama, N. 2018. Serosurvey of Babesia bovis and Babesia bigemina in cattle in Mongolia. Vet. Parasitol. Reg. Stud. Reports 13, 85–91.
  25. Sivakumar, T., Lan, D.T.B., Long, P.T., Viet, L.Q., Weerasooriya, G., Kume, A., Suganuma, K., Igarashi, I., Yokoyama, N. 2018. Serological and molecular surveys of Babesia bovis and Babesia bigemina among native cattle and cattle imported from Thailand in Hue, Vietnam. J. Vet. Med. Sci. 80, 333–336.
WOAH Reference Centres