Staff

ISHII Toshiaki

Professor

Theme

I work on elucidating the physiological development of the brain and nervous system and the pathogenic mechanisms of cerebral neurodegenerative diseases, such as Parkinson's and Alzheimer's diseases. I use mice, rats and other experimental animals and cultured nerve cells to study using pharmacology, biochemistry, molecular biology, morphology and other methods.

My Dream

Elucidation of higher brain functions and development of drugs for cerebral neurodegenerative diseases
  • Pharmacology Laboratory

Belongs

Research Department, Department of Veterinary Medicine, Division of Veterinary Sciences, Section of Physiology and Pharmacology

Diagnostic Center for Animal Health and Food Safety, Director General

Faculty (Unit)

Veterinary Medicine Program

Grad school (Course)

Doctoral Program of Veterinary Science

Field of research Neuroscience, Pharmacology, Biiochemistry, Molecular biology, Neurochemistry, Clanial nerve phisiology
Keyword Parkinson disease, Dementia, Fixation and removal of memory, Feeding instinct, Depression, Fear memory, Growth of brain in weaning period, Plasticity of nerve, Hippocampus, Neurogenesis, Mouse

Introduction

I mainly work on elucidating the physiological development of the brain and central nervous system and the pathogenic mechanisms of cerebral neurodegenerative diseases, such as Parkinson's and Alzheimer's diseases. For the above, I use mice, rats and other experimental animals, and cultured nerve cells, and I work to develop treatment methods. Regarding cerebral physiology, I focus on the brains of mammal infants in the weaning period, which is when they grow rapidly in a short period of time. I conduct research to elucidate the molecular mechanisms behind the development of the feeding instinct that becomes apparent after weaning (the innate ability to change from the passive diet behavior of suckling during the mother's lactation period to the spontaneous dietary behavior of finding and obtaining food independently) and behind the acquisition of nocturnal behavior (the completion of nocturnal daily rhythm indicated by adult animals). Concerning brain disorders, I work to elucidate the pathogenic mechanisms seen in cognitive disorders that feature in Parkinson's disease and to develop treatments for those disorders.
Academic degree Ph.D. Agr.
License Veterinarian
Room address General Research Building 1
Mail address ishii atmark obihiro.ac.jp

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