研究業績

    研究プロジェクトリーダー 五十嵐郁男

H15 (2003) 年度

学術論文(国際学術雑誌)

1.Nagai, A., Yokoyama, N., Matsuo, T., Bork, S., Hirata, H., Xuan, X., Zhu, Y., Claveria, F.G., Fujisaki, K. and Igarashi, I. 2003. Growth-inhibitory effects of artesunate, pyrimethamine, and pamaquine against Babesia equi and Babesia caballi in vitro cultures. Antimicrob. Agents. Chemother. 47:800-803.

2.Yokoyama, N., Bork, S., Nishisaka, M., Hirata, H., Matsuo, T., Inoue, N., Xuan, X., Suzuki, H., Sugimoto, C. and Igarashi, I. 2003. Roles of the Maltese cross form in the development of parasitemia and protection against Babesia microti infection in mice. Infect. Immun. 71:411-417.

3.Mulenga, A., Tsuda, A., Onuma, M. and Sugimoto, C. 2003. Four serine proteinase inhibitors (serpin) from the brown ear tick, Rhiphicephalus appendiculatus; cDNA cloning and preliminary characterization. Insect. Biochem. Mol. Biol. 33:267-276.

4.Hirata, H., Xuan, X., Yokoyama, N., Nishikawa, Y., Fujisaki, K., Suzuki, N. and Igarashi, I. 2003. Identification of a specific antigenic region of the P82 protein of Babesia equi and its potential use in serodiagnosis. J. Clin. Microbiol. 41:547-551.

5.Huang, X., Xuan, X., Yokoyama, N., Xu, L., Suzuki, H., Sugimoto, C., Nagasawa, H., Fujisaki, K. and Igarashi, I. 2003. High-level expression and purification of a truncated merozote antigen-2 of Babesia equi in Escherichia coli and its potential for immunodiagnosis. J. Clin. Microbiol. 41:1147-1151.

6.You, M., Xuan, X., Tsuji, N., Kamio, T., Taylor, D., Suzuki, N. and Fujisaki, K. 2003. Identification and molecular characterization of a chitinase from the hard tick Haemaphysalis longicornis. J. Biol. Chem. 278: 8556-8563.

7.Takashima, Y., Xuan, X., Kimata, I., Iseki, M., Kodama, Y., Nagane, N., Nagasawa, H., Matsumoto, Y., Mikami, T. and Otsuka, H. 2003. Recombinant bovine herpesvirus-1 (BHV-1) expressing P23 protein of Cryptosporidium parvum induces neutralizing antibodies in rabbits. J. Parasitol. 89: 276-282.

8.Makala, L., Reyes, J.C., Nishikawa, Y., Tsushima, Y., Xuan, X., Huang, X., Battsetseg, B., Matsuo, T. and Nagasawa, H. 2003. Phenotype and function of murine discrete Peye’s patch macrophage deriveddendric cells. J. Vet. Med. Sci. 65: 491-499.

9.Maruyama, S., Kabeya, H., Nakao, R., Tanaka, S., Sakai, T., Xuan, X., Katsube, Y. and Mikami, T. 2003. Seroprevalence of Bartonella henselae, Toxoplasma gondii, FIV and FeLV infections in domestic cats in Japan. Microbiol. Immunol. 47: 147-153.

10.Makala, L., Reyes, J.C., Nishikawa, Y., Tsushima, Y., Xuan, X., Huang, X. and Nagasawa, H. 2003. A comparison of the phenotype of dendritic cells derived from discrete Peyerʼs patch macrophages of non-infected and Toxoplasma gondii infected mice. J. Vet. Med. Sci. 65: 591-597.

11.Tsushima, Y., Karanis, P., Kamada, T., Xuan, X., Makala, L., Tohya, Y., Akashi, H. and Nagasawa, H. 2003. Viability and infectivity of Cryptosporidium parvum oocysts detected in river water in Hokkaido, Japan. J. Vet. Med. Sci. 65: 585-589.

12.Fukumoto, S., Xuan, X., Kadota, K., Igarashi, I., Sugimoto, C., Fujisaki, K., Nagasawa, H., Mikami, T. and Suzuki, H. 2003. High-level expression of truncated major surface antigen P50 of Babesia gibsoni in insect cells by baculovirus and evaluation of its immunogenicity. Clin. Diagn. Lab. Immunol. 10: 596-601.

13.Hemberger, M., Nozaki, T., Winterhager, E., Yamamoto, H., Nakagama, H., Kamada, N., Suzuki, H., Ohta, T., Ohki, M., Masutani, M. and Cross, J.C. 2003. Parp1-deficiency induces differentiation of ES cells into trophoblast derivatives. Dev. Biol. 257: 371-381.

14.Takeiri, A., Mishima, M., Tanaka, K., Shioda, A., Ueda, O., Suzuki H., Inoue, M., Masumura, K. and Nohmi, T. 2003. Molecular characterization of mitomycin C-induced large deletions and tandem-base substitutions in the bone marrow of gpt delta transgenic mice. Chem. Res. Toxicol. 16: 171-179.

15.Nozaki, T., Fujihara, H., Watanabe, M., Tsutsumi, M., Nakamoto, K., Kusuoka, O., Kamada, N., Suzuki, H., Nakagama, H., Sugimura, T. and Masutani, M. 2003. Parp-1 deficiency implicated in colon and liver tumorigenesis induced by Azoxymethane. Cancer Sci. 94: 497-500.

16.Shibata, A., Masutani, M., Nozaki, T., Kamada, N., Fujihara, H., Masumura, K., Nakagama, H., Sugimura, T., Kobayashi, S., Suzuki, H. and Nohmi, T. 2003. Improvement of the Spi- assay for mutagenesis in gpt delta mice by including magnesium ions during plaque formation. Environ. Mol. Mutagen. 41: 370-372.

17.Ueda, O., Yorozu, K., Kamada, N., Jishage, K., Toyoda, Y. and Suzuki, H. 2003. Possible expansion of “window of implantation” in pseudopregnant mice: Time of implantation of embryos at different stages of development transferred into the same recipient. Biol. Reprod. 69: 1085-1090.

18.Nishikawa, Y., Inoue, N., Makala, L. and Nagasawa, H. 2003. A role for balance of interferon-gamma and interleukin- 4 production in protective immunity against Neospora caninum infection. Vet. Parasitol. 116: 175-184.

19.Bannai, H., Sakurai, T., Inoue, N., Sugimoto, C. and Igarashi, I. 2003. Cloning and expression of a mitochondrial heat shock protein 70 of Trypanosoma congolense and potential use as a diagnostic antigen. Clin. Diagn. Lab. Immunol. 10: 926-933.

20.Matsuo, T., Sato, M., Inoue, N., Yokoyama, N., Taylor, D. and Fujisaki, K. 2003. Morphological studies on the extracellular structure of midgut of a tick, Haemaphysalis longicornis (Acari: Ixodidae). Parasitol. Res. 90: 243-248.

21.Bork, S., Yokoyama, N., Matsuo, T., Claveria, F. G., Fujisaki, K. and Igarashi, I. 2003. Clotrimazole, Ketoconazole, and Clodinafop-propargyl as Potent Growth Inhibitors of Equine Babesia Parasites in In vitro Cultures. J. Parasitol. 89: 604-606.

22.Bork, S., Yokoyama, N., Matsuo, T., Claveria, F. G., Fujisaki, K. and Igarashi, I. 2003. Clotrimazole, ketoconazole, and clodinafop-propargyl inhibit the in vitro growth of Babesia bigemina and Babesia bovis (Phylum Apicomplexa). Parasitology 127: 311-315.

23.Furuno-Fukushi, I., Masumura, K., Furuse, T., Noda, Y., Takahagi, M., Saito, Y., Suzuki, H., Wynshaw-Boris, A. and Nohmi, K. 2003. Effect of Atm disruption on spontaneously arising and radiation-induced deletion mutations in mouse liver. Rediat. Res. 160: 549-558.

24.Xu, Y., Zhang, S., Huang, X., Bayin, C., Xuan, X., Igarashi, I., Fuzisaki, K., Kabeya, H., Maruyama, S. and Mikami, T. 2003. Seroepidemiologic studies on Babesia equi and Babesia caballi infections in horses in Jilin province of China. J. Vet. Med. Sci. 65: 1015-1017.

25.Fukumoto, S., Xuan, X., Inoue, N., Igarashi, I., Sugimoto, C., Fujisaki, K., Nagasawa, H., Mikami, T. and Suzuki, H. 2003. Molecular characterization of a gene encoding 29 kDa cytoplasmic protein of Babesia gibsoni and evaluation of its diagnostic potentiality. Mol. Biochem. Parasitol. 131: 129-136.

26.Kuboki, N., Inoue, N., Sakurai, T., Di Cello, F., Grab, D. J., Suzuki, H., Sugimoto, C. and Igarashi, I. 2003. Loop-mediated isothermal amplification (LAMP) and its application for the detection of African trypanosomes. J. Clin. Microbiol. 41: 5517-5524.

27.Nishikawa, Y., Xuan, X., Makala, L., Vielemeyer, O., Joiner, K.A. and Nagasawa, H. 2003. Characterization of Toxoplasma gondii engineered to express mouse interferon-gamma. Int. J. Parasitol. 33: 1525-1535.

28.Makino, S-I. and Cheun, H-I. 2003. Application of the real-time PCR for the detection of airborne microbial pathogens in reference to the anthrax spores. J. Microbiol. Meth. 53: 141-147.

29.Makino, S-I., Tobe, T., Asakura, H., Watarai, M., Ikeda, T., Takeshi, K. and Sasakawa, C. 2003. Distribution of the secondary type III secretion system locus found in enterohemorrhagic Escherichia coli O157:H7 among Shiga toxin-producing E. coli. J. Clin. Microbiol. 41: 2341-2347.

30.Kim, S., Watarai, M., Kondo, Y., Erdenebaatar, J., Makino, S-I. and Shirahata, T. 2003. Isolation and characterization of mini-Tn5Km2 insertion mutants of Brucella abortus deficient in internalization and intracellular growth in HeLa cells. Infect. Immun. 71: 3020-3027.

31.Watarai, M., Kim, S., Erdenebaatar, J., Makino, S-I.,Horiuchi, M., Shirahata, T., Sakaguchi, S. and Katamine. S. 2003. Cellular prion protein promotes Brucella infection into macrophages. J. Exp. Med. 198: 5-17.

32.Cheun, H-I., Makino, S-I., Watarai, M., Erdenebaatar, J., Kawamoto, K. and Uchida, I. 2003. Rapid and effective detection of anthrax spores in soil by PCR. J. Appl. Microbiol. 95: 728-733.

33.Erdenebaatar, J., Bayarsaikhan, B., Watarai, M., Makino, S-I. and Shirahata, T. 2003. Enzyme-linked immunosorbent assay to differentiate the antibody responses of animals infected with Brucella species from those of animals infected with Yersinia enterocolitica O9. Clin. Diagn. Lab. Immunol. 10: 710-714.

34.Satoh, E., Ishii, T. and Nishimura, M. 2003. Palytoxininducedincrease in cytosolic-free Ca2+ in mouse spleen cells. Eur. J. Pharmacol. 465: 9-13.

35.Ducusin, R. J. T., Uzuka, Y., Satoh, E., Otani, M., Nishimura, M., Tanabe, S. and Sarashina, T. 2003. Effects of extracellular Ca2+ on phagocytosis and intracellular Ca2+ concentrations in polymorphonuclear leukocytes of postpartum dairy cows. Res.Vet. Sci. 75: 27-32.

36.Takeda, K., Omata, Y., Koyama, T., Ohtani, M., Kobayashi, Y., Furuoka, H., Matsui, T., Maeda, R. and Saito, A. 2003. Increase of Th1 type cytokine mRNA expression in peripheral blood lymphocytes of calves experimentally infected with Cryptospridium parvum. Vet. Parasitol. 113: 327-331.

37.Hanada, S., Umemoto, Y., Omata, T., Koyama, T., Kobayashi, Y., Furuoka, H., Matsui, T., Maeda, R. and Saito, A. 2003. Eimeria stiedai merozoite 49-kDa soluble antigen induces protektion against infection. J. Parasitol. 89: 613-617.

38.Koyama, T., Omata, Y. and Saito, A. 2003. Changes in salivary cortisol concentrations during a 24-hour period in dogs. Horm. Metab. Res. 35: 355-357.

39.Maeda, A., Lee, B.-H., Yoshimatsu, K., Saijo, M., Kurane, I., Arikawa, J. and Morikawa, S. 2003. The intracellular association of the nucleocapsid protein (NP) of hantaan virus (HTNV) with small ubiquitinlike modifier-1 (SUMO-1) conjugating enzyme 9 (Ubc9). Virology 305: 288-297.

40.Qing, T., Saijo, M., Han, L., Niikura, M., Maeda, A., Ikegami, T., Xinjung, W., Kuran, I. and Morikawa, S. 2003. Detection of immunoglobulin G to Crimean- Congo hemorrhagic fever virus in sheep sera by recombinant nucleoprotein-based enzyme-linked immunosorbent and immunofluorescence assays. Journal of Virological Methods 108: 111-116.

41.Qing, T., Saijo, M., Zhang, Y., Asiguma, M., Tianshu, D., Han, L., Shimayi, B., Maeda, A., Kurane, I. and Morikawa, S. 2003. A patient with Crimean-Congo hemorrhagic fever serologically diagnosed by recombinant nucleoprotein-based antibody detection systems. Clin. Diagn. Lab. Immunol. 10: 489-491.

42.Lee, B.-H., Yoshimatsu, K., Maeda, A., Ochiai, K., Morimatsu, M., Araki, K., Ogino, M., Morikawa, S. and Arikawa, J. 2003. Association of the nucleocapsid protein of the Seoul and Hantaan hantaviruses with small ubiquitin-like modifier-1-related molecules. J. Virus Research. 98: 83-91.

43.Lee, I., Yamagishi, N., Oboshi, K., Yamada, H. 2003 Effect of epidural fat on xylazine-induced dorsolumbar epidural analgesia in cattle. Vet. J. 165: 330-332. 44.Lee, I., Yamagishi, N., Oboshi, K., Yamada, H. 2003. Antagonistic effects of intravenous or epidural atipamezole on xylazine-induced dorsolumbar epidural analgesia in cattle. Vet. J. 166: 194-197.

45.Naya, Y., Horiuchi, M., Ishiguro, N. and Shinagawa, M. 2003. Bacteriological and genetic assessment of game meat from Japanese wild boars. J. Agric. Food. Chem. 51(2): 345-349.

46.Gombojav, A., Ishiguro, N., Horiuchi, M., Serjmayadag, D., Byambaa, B. and Shinagawa, M. 2003. Amino acid polymorphisms of PrP gene in Mongolian sheep. J. Vet. Med. Sci. 65(1): 75-81.

47.Gombojav, A., Shimauchi, I., Horiuchi, M., Ishiguro, N., Shinagawa, M., Kitamoto, T., Miyoshi, I., Mohir, S. and Takata, M. 2003. Susceptibility of Transgenic Mice Expressing Chimeric Sheep, Bovine and Human PrP Genes to Sheep Scrapie. J. Vet. Med. Sci. 65(3): 341-347.

48.Acosta, TJ., Hayashi, KG., Ohtani, M., Miyamoto, A. 2003. Local changes in blood flow within the preovulatory follicle wall and early corpus luteum in cows. Reproduction 125: 759-767.

49.Wijayagunawardane, MP., Gabler, C., Killian, G. and Miyamoto, A. 2003. Tumor necrosis factor alpha in the bovine oviduct during the estrous cycle: messenger RNA espression and effect on secretion of prostaglandins, endothelin-1, and angiotensin II. Biol. Reprod. 69: 1341-1346.

50.Hayashi, K., Acosta, TJ., Berisha, B., Kobayashi, S., Ohtani, M., Schams, D. and Miyamoto, A. 2003. Changes in prostaglandin secretion by the regressing bovine corpus luteum. PG & Other Lipid Med. 70: 339-349.

51.Hayashi, K., Miyamoto, A., Konari, A., Ohtani, M. and Fukui, Y. 2003. Effect of local interaction of reactive oxygen species with prostaglandin F (2alpha) on the release of progesterone in ovine corpora lutea in vivo. Theriogenology 59: 1335-1344.

52.Tetsuka, M., Yamamoto, S., Hayashida, N., Hayashi, KG., Hayashi, M., Acosta, TJ. and Miyamoto, A. 2003. Expression of 11beta-hydroxysteroid dehydrogenases in bovine follicle and corpus luteum. J. Endocrinol. 177: 445-452.

53.Tetsuka, M., Nancarrow, CD. 2003. Immunization against 5a-androstane-3alpha, 17beta-diol affects ovarian folliculogenesis in Merino ewes. Theriogenology 60: 307-317.

54.Nou, V., Inoue, H., Lee, HG., Matsunaga, N., Kuwayama, H. and Hidari, H. 2003. Effect of twice daily administration of GH-releasing peptide-2 for 10 days on growth performance, plasma GH responses and insulin- like growth factor-1 consentrations in swine. Asian-Australian J. Anim. Sci. 16: 1193-1198.

55.Nou, V., Tomoshi, K., Inoue, H., Matsunaga, N., Kuwayama, H. and Hidari, H. 2003. Effect of exogenous porcine GH administration on GH responses to GHreleasing peptide-2 and GH-releasing hormone in swine. Asian-Australian J. Anim. Sci. 16: 1188-1192.

56.Hayashi, KG., Acosta, TJ., Tetsuka, M., Berisha, B., Matsui, M., Schams, D., Ohtani, M. and Miyamoto, A. 2003. Involvement of angiopoietin-tie system in bovine follicular development and atresia: messenger RNA expression in theca interna and effect on steroid secretion. Biol. Reprod. 69: 2078-2084.

57.Ahn, DH., Shimada, K., Takahashi, K. 2003. Relationship between weakening of Z-disks and liberation of phospholipids during postmortem aging of pork and beef. J. Food. Sci. 68: 94-98.

58.Han, KH., Fukushima, M., Kato, T., Kojima, M., Ohba, K., Shimada, K., Sekikawa, M., Nakano, M. 2003. Enzyme- resistant fractions of beans lowered serum cholesterol, and increased sterolexcretions and hepatic mRNA levels in rats. Lipids. 38: 919-924.

59.Han, KH., Fukushima, M., Shimizu, K., Kojima, M., Ohba, K., Tanaka, A., Shimada, K., Sekikawa, M., Nakano, M. 2003. Resistant starches of beans reduce the serum cholesterol concentration in rats. J. Nutr. Sci. Vitaminol. 49:281-286.

60.Suzuki, M., Ushijima, N., Kohno, A., Sawa, Y., Yoshida, S., Sekikawa, M., Ohtaishi, N. 2003. Plastic casts and confocal laser scanning microscopy applied to observation of enamel tubules in red Kangaroo (Macropus rufus) Ana. Sci. Int. 78: 53-61.

61.Topping, DL., Fukushima, M. and Bird, AR. 2003. Resistant starch as a prebiotic and synbiotic: state of the art. Proc. Nutr. Sci.

62: 171-176. 62.Urashima, T., Nakamura, T., Yamaguchi, K., Munakata, J., Arai, I., Saito, T., Lydersen, C., Kovacs, KM. 2003. Chemical characterization of the oligosaccharides in milk of high Arctic harbour seal (Phoca vitulina vitulina). Comp. Biochem. Physiol. 135A: 549-563.

63.Pelletier, I., Hashidate, T., Urashima, T., Nishi, N., Nakamura, T., Futai, M., Arata, Y., Kasai, K., Hirashima, M., Hirabayashi, J., Sato, S. 2003. Specific recognition of Leishmania major poly-β-galactosyl epitopes by galectin-9. J. Biol. Chem. 278: 22223-22230.

64.Nozaki, H., Matsuzawa, T., Nakamura, T., Arai, I., Urashima, T. 2003. Are there two forms of β2-Nacetylglucosaminyltransferase in rat testicular and epididymal fluids? Biochim. Biophys. Acta 1649: 140-145.

65.Nakamura, T., Urashima, T., Mizukami, T., Fukushima, M., Arai, I., Senshu, T., Imazu, K., Nakao, T., Saito, T., Zhiyong, Y., Hong, Z., Kongju, W. 2003. Compsition and oligosaccharides of a milk sample of the giant panda, Ailuropada melanoleuca. Comp. Biochem. Physiol. 135B: 439-448.

66.Nakamura, T., Kawase, H., Kimura, K., Watanabe, Y., Ohtani, M., Arai, I., Urashima, T. 2003. Concentrations of sialyloligosaccharides in bovine colostrum and milk during the prepartum and early lactation. J. Dairy Sci. 86: 1315-1320.

67.Sumiyoshi, W., Urashima, T., Nakamura, T., Arai, I., Saito, T., Tsumura, N., Wang, B., Brand-Miller, J., Watanabe, Y., Kimura, K. 2003. Determination of each neutral oligosaccharide in Japanese women milk during the course of lactation. Br. J. Nutr. 89: 61-69.

68.Urashima, T., Nagata, H., Nakamura, T., Arai, I., Saito, T., Imazu, K., Hayashi, T., Derocher, AE., Wiig, O. 2003. Differences in oligosaccharide pattern of a sample of polar bear colostrum and mid-lactation milk. Comp. Biochem. Physiol. 136B: 887-896.

69.Sumiyoshi, W., Urashima, T., Nakamura, T., Arai, I., Nagasawa, T., Saito, T., Tsumura, N., Wang, B., Brand-Miller, J., Watanabe, Y., Kimura, K. 2003. Sialyl oligosaccharides in the milk of Japanese women: changes in concentration during the course of lactation. J. Appl. Glycosci. 50: 461-467.

70.Huang, X., Xuan, X., Hirata, H., Yokoyama, N., Xu, L., Suzuki, N., and Igarashi, I. 2004. A rapid immunochromatographic test with recombinant SAG2 for the detection of antibodies against Toxoplasma gondii in cats. J. Clin. Microbiol. 42: 351-353.

71.Huang, X., Xuan, X., Xu, L., Zhang, S., Yokoyama, N., Suzuki, N., and Igarashi, I. 2004. Development and evaluation of an immunochromatographic test for the rapid detection of Babesia equi infection in horses. J. Clin. Microbiol. 42: 359-361.

72.Bork, S, Yokoyama, N., Ikehara, Y., Kumar, S., Sugimoto, C. and Igarashi, I. 2004. Growth inhibitory effect of heparin on Babesia parasites. Antimicrobiol. Agent. Chemotherap. 48: 236-241.

73.Tamaki, Y., Hirata, H., Takabatake, N., Bork, S., Yokoyama, N., Xuan, X., Fujisaki, K., Igarashi, I. 2004. Molecular cloning of a Babesia caballi gene encoding 134 kDa protein and evaluation of its diagnostic potential in an enzyme-linked immunosorbent assay. Clin. Diagn. Lab. Immunol. 11: 211-215.

74.Kaneko, Y., Takashima, Y., Xuan, X., Nagasawa, H., Mikami, T. and Otsuka, H. 2004. Natural IgM antibodies in sera from various animals except cat kill Toxoplasma gondii by activating complement calassical pathway. Parasitology 128: 123-129.

75.Boonchit, S., Xuan, X., Yokoyama, N., Goff, W.L., Waghela, S.D., Wagner, G., Igarashi, I. 2004. An improvedenzyme-linked immunosorbent assay using C-terminal truncated recombinant antigens of Babesia bovis rhoptry-associated protein-1 for the detection of specific antibodies. J. Clin. Microbiol. 42: 1601-1604.

76.Kawase, Y., Aoki, Y., Kamada, N., Jishage, K., Suzuki, H. 2004. Comparison of fertility between intracytoplasmic sperm injection and in vitro fertilization with a partial zona pellucida incision by using a Piezo-micromanipulator in cryopreserved inbred mouse spermatozoa. Contemp. Topics Lab. Anim. Sci. 43: 21-25.

77.Harakawa, S., Inoue, N., Saito, A., Doge, F., Nagasawa, H., Suzuki, N. and Martin, D. E. 2004. 60 Hz electric field upregulates cytosolic Ca2+ level in mouse splenocytes stimulated by lectin. Bioelectromagnetics 25: 204-210.

78.Kumar, S., Yokoyama N., Kim J-Y, Huang X., Inoue N., Xuan X., Igarashi I. and Sugimoto C. 2004. Expression of Babesia equi EMA-1 and EMA-2 during merozoite developmental stages in erythrocyte and their interaction with erythrocyte membrane proteins. Mol. Biochem. Parasitol. 133: 221-227.

79.Fukumoto, S., Xuan, X., Takabatake, N., Sugimoto, C., Fujisaki, K., Nagasawa, H., Mikami, T. and Suzuki, H. 2004. Inhibitory effect of antiserum to surface antigen P50 of Babesia gibsoni on growth of parasites in canine red blood cell-substituted severe combined immunodeficiency mice. Infect. Immun. 72: 1795-1798.

80.Lee, I., Yamagishi, N., Oboshi, K., Yamada, H. 2004. Eliminating the effect of the epidural fat from dorsolumbar epidural analgesia in cattle. Veterinary Anaesthesia and Analgesia 31: 86-89.

81.Kim, C., Umetani, A., Matsui, T., Ishiguro, N., Shinagawa, M. and Horiuchi, M. 2004. Antigenic characterization of an abnormal isoform of prion protein using a new diverse panel of monoclonal antibodies. Virology 320: 40-51.

82.Ohtani, M., Takase, S., Wijayagunawardane, MPB., Tetsuka, M., Miyamoto, A. 2004. Local interaction of prostaglandin F2α with endothelin-1 and tumor necrosis factor-α on the release of progesterone and oxytocin in ovine corpora lutea in vivo: a possible implication for a luteoly tic cascade. Reproduction 127: 117-124.

著書・総説・学術論文(国内学術雑誌)

1.寺社下浩一,鈴木宏志.2003.ポイツイエガー症候群 の原因遺伝子LKB1の生理的機能.細胞 35: 22-25.

2.鈴木宏志.2003.スカベンジャーレセプターと病原体 認識.医学のあゆみ 205:17-21.

3.牧野壮一.2003. 炭疽菌の特性と病原性. クリーンテ クノロジー 13:43-45.

4.牧野壮一.2003.人と動物の共通感染症としての炭 疽.動物協会会報.36(1):59-62.

5.牧野壮一.2003.炭疽菌.理解して実践する感染症診 療・投薬ガイド.「総合臨牀」増刊号 52:447-452.

6.牧野壮一.2003.細菌の遺伝学 グラム陽性桿菌 バ シラス属(炭疽菌).新世紀の感染症学(下)-ゲノ ム・グローバル時代の感染症アップデートー.日本臨 牀 増刊号 61:677-682.

7.牧野壮一.2003.炭疽菌(Bacillus anthracis)病原菌 の今日的意味(松本慶蔵編).272-280.医薬ジャーナ ル 大阪.

8.牧野壮一.2003.炭疽.実践抗生物質・抗菌薬療法ガ イド.Medical Practice Vol 20 臨時増刊. 285-287.

9.牧野壮一.2003.炭疽菌感染症への対応.臨床医  29:1312-1313.

10.牧野壮一.2003.バシラス属(好気性有芽胞菌)と感 染症 獣医微生物学 第二版(見上毅編).93-96.文 永堂出版.東京.

11.牧野壮一.2003.リステリア属と感染症 獣医微生物 学 第二版(見上毅編).99-100.文永堂出版 東京.

12.前田秋彦,倉根一郎.2003.ニパウイルス感染症  「動物由来感染症-その診断と対策」(神山恒夫, 山田 章雄編集).101-105.真興交易.東京.

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特 許

1.鈴木寛,長澤秀行,五十嵐慎,田中一郎,鈴木直義, 五十嵐郁男.抗マラリア剤(特許出願番号:2005- 077849).

2.Hiromi Ikadai, Ikuo Igarashi, Naoyoshi Suzuki, Hideyuki Nagasawa, Kozo Fujisaki, Takeshi Mikami, Gene encoding merozoite protein of Babesia caballi, recombinantprotein obtained therefrom and utlization thereof. US6, 855, 319 B1, Feb 15, 2005